THE SHORT VERSION
Rome to Brindisi at a glance.
- From
- Rome Roma
- To
- Brindisi
- Road distance
- About 616 km
- Straight line
- 477 km
- Car time, no stops
- ~6 h 30 min buses take longer
- Return route
- Brindisi to Rome →
Ready to travel from Rome to Brindisi?
Check live availability, fares and departure times with 12Go.
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Rome
Rome is Italy's biggest coach destination, with domestic routes and overnight connections to France, Switzerland and Germany. Most long-distance buses use the coach terminal next to Tiburtina station.
- Roma Tiburtina coach terminal
Next to Tiburtina railway station (metro line B). FlixBus and most long-distance coaches. - Termini and airport stops
Airport shuttles and some services use Termini station and the airports.
Arriving in Brindisi
Ask the seller where the service ends in Brindisi. A town-name stop can be a bus station some way from the centre, and the last stretch to your accommodation is usually up to you.
Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
KEEP GOING
From Brindisi, the road continues.
Other ways to reach Brindisi
More buses from Rome
GOOD QUESTIONS
Before you take your seat.
How far is Rome from Brindisi by road?+
About 616 km by road (477 km in a straight line). Distance is an OpenStreetMap routing estimate, not an operator figure.
How long does the bus from Rome to Brindisi take?+
We don't publish timetables. As a guide, the drive takes roughly 6 h 30 min by car without stops; bus journeys are usually longer. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Rome?+
It depends on the operator. Main options in Rome include Roma Tiburtina coach terminal, Termini and airport stops, and many tourist companies collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Brindisi to Rome?+
Yes, 12Go also lists services in the opposite direction. See our Brindisi to Rome guide.
Where does the bus from Rome arrive in Brindisi?+
It depends on the operator. Some services end at the local bus station, others at an office or a stop on the main road. Ask the seller for the drop-off address before you book.
What kind of bus runs from Rome to Brindisi?+
It varies by operator and departure. Routes in this region are served by a mix of sleeper buses, seated coaches and smaller limousine vans. Check the vehicle type, seat layout and luggage allowance for your departure on 12Go before you book.
Can I book the Rome to Brindisi bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Brindisi by bus?+
Direct buses from Brindisi include Naples, Milan, Lecce, Taranto, Bari and more. See all connections on our Brindisi bus page.
Still deciding? Check today's departures, then book your seat.
Book Rome → Brindisi on 12GoFOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Rome to Brindisi bus route listing ↗Wikivoyage: Rome (Get in) ↗How BusConnects uses sources →