THE SHORT VERSION
Rome to Lyon at a glance.
- From
- Rome Roma
- To
- Lyon
- Road distance
- About 992 km
- Straight line
- 749 km
- Car time, no stops
- ~10 h 45 min buses take longer
- Return route
- Lyon to Rome →
- Border
- Italy → France. Schengen: carry ID
Ready to travel from Rome to Lyon?
Check live availability, fares and departure times with 12Go.
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Rome
Rome is Italy's biggest coach destination, with domestic routes and overnight connections to France, Switzerland and Germany. Most long-distance buses use the coach terminal next to Tiburtina station.
- Roma Tiburtina coach terminal
Next to Tiburtina railway station (metro line B). FlixBus and most long-distance coaches. - Termini and airport stops
Airport shuttles and some services use Termini station and the airports.
Arriving in Lyon
Perrache is linked to the city by metro line A and trams.
- Lyon Perrache bus station · Gare routière de Perrache
Next to Perrache railway station. FlixBus and other long-distance services.

Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
- Some services also stop at Lyon Part-Dieu or Lyon Saint-Exupéry airport.
KEEP GOING
From Lyon, the road continues.
Other ways to reach Lyon
More buses from Rome
GOOD QUESTIONS
Before you take your seat.
How far is Rome from Lyon by road?+
About 992 km by road (749 km in a straight line). Distance is an OpenStreetMap routing estimate, not an operator figure.
How long does the bus from Rome to Lyon take?+
We don't publish timetables. As a guide, the drive takes roughly 10 h 45 min by car without stops; bus journeys are usually longer. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Rome?+
It depends on the operator. Main options in Rome include Roma Tiburtina coach terminal, Termini and airport stops, and many tourist companies collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Lyon to Rome?+
Yes, 12Go also lists services in the opposite direction. See our Lyon to Rome guide.
Where does the bus from Rome arrive in Lyon?+
It depends on the operator. In Lyon, services use Lyon Perrache bus station. Perrache is linked to the city by metro line A and trams.
How do I get from the bus stop to the centre of Lyon?+
Perrache is linked to the city by metro line A and trams.
What kind of bus runs from Rome to Lyon?+
It varies by operator and departure. Routes in this region are served by a mix of sleeper buses, seated coaches and smaller limousine vans. Check the vehicle type, seat layout and luggage allowance for your departure on 12Go before you book.
Can I book the Rome to Lyon bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Lyon by bus?+
Direct buses from Lyon include Marseille, Zurich, Milan, Paris, Nice and more. See all connections on our Lyon bus page.
Do I need my passport on the bus from Rome to Lyon?+
Italy and France are both in the Schengen area, so there are usually no routine border checks. Carry your passport or national ID card anyway: spot checks happen and operators may ask for ID.
Still deciding? Check today's departures, then book your seat.
Book Rome → Lyon on 12GoFOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Station information reviewed 2026-10-09. Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Rome to Lyon bus route listing ↗Wikivoyage: Rome (Get in) ↗Wikivoyage: Lyon (Get in) ↗How BusConnects uses sources →