THE SHORT VERSION
Rome to Sicily at a glance.
- From
- Rome Roma
- To
- Sicily Isola di Sicilia
- Straight line
- 511 km
- Return route
- Sicily to Rome →
Ready to travel from Rome to Sicily?
Check live availability, fares and departure times with 12Go.
THE DETAILS THAT MAKE A DIFFERENCE
Right place. Right bus. Better start.
Leaving Rome
Rome is Italy's biggest coach destination, with domestic routes and overnight connections to France, Switzerland and Germany. Most long-distance buses use the coach terminal next to Tiburtina station.
- Roma Tiburtina coach terminal
Next to Tiburtina railway station (metro line B). FlixBus and most long-distance coaches. - Termini and airport stops
Airport shuttles and some services use Termini station and the airports.
Arriving in Sicily
Ask the seller where the service ends in Sicily. A town-name stop can be a bus station some way from the centre, and the last stretch to your accommodation is usually up to you.
Keep the essentials offline
Save your ticket, the exact meeting point and the operator's phone number before you set off. Follow the check-in time on your confirmation.
KEEP GOING
From Sicily, the road continues.
This trip includes a boat crossing. For ferry routes and timetables, see our sister site FerryConnect.
Other ways to reach Sicily
More buses from Rome
GOOD QUESTIONS
Before you take your seat.
How long does the bus from Rome to Sicily take?+
Journey times depend on the service and any boat connection. Check the duration of your chosen departure on 12Go before booking.
Where does the bus leave from in Rome?+
It depends on the operator. Main options in Rome include Roma Tiburtina coach terminal, Termini and airport stops, and many tourist companies collect from offices or hotels. Your ticket shows the exact boarding point.
Is there a bus back from Sicily to Rome?+
Yes, 12Go also lists services in the opposite direction. See our Sicily to Rome guide.
Where does the bus from Rome arrive in Sicily?+
It depends on the operator. Some services end at the local bus station, others at an office or a stop on the main road. Ask the seller for the drop-off address before you book.
What kind of bus runs from Rome to Sicily?+
Tickets to Sicily usually combine a bus or van with a boat. The vehicle type, seat style and boat connection are shown for each departure on 12Go.
Can I book the Rome to Sicily bus online?+
Yes. 12Go lists departures on this route. You choose a date, compare operators and pay online, and the provider issues the ticket. BusConnects doesn't sell tickets itself.
Where can I go next from Sicily by bus?+
Direct buses from Sicily include Florence, Milan, Naples, Venice, Bari and more. See all connections on our Sicily bus page.
Does the trip to Sicily include a ferry?+
Yes, Sicily is an island, so the journey includes a boat crossing. Check whether your ticket covers the boat and the transfer from the pier, and allow for weather delays.
Still deciding? Check today's departures, then book your seat.
Book Rome → Sicily on 12GoFOLLOW THE INFORMATION
Clear sources. Better decisions.
Route listed in 12Go's public route index (checked 2026-10-09). Distance: OpenStreetMap data via OSRM (approximate driving distance). Listings change and are not live inventory. Confirm the departure, pickup, price and conditions before paying.
12Go: Rome to Sicily bus route listing ↗Wikivoyage: Rome (Get in) ↗How BusConnects uses sources →